The church, in the centre of Viterbo, dates back to 1510. Built by the will of the proton-taro of Leo X John the Baptist Almadiani, the aim was to assign in his city a convent and a church to the order of the Carmelites.
The suggestive structure was realized by the architect Bernardino da Viterbo. The interior of the church is divided into three naves by high peperino columns. A harmonious style, typical of Renaissance architecture, characterizes the church of the Almadians.
The bell tower, decorated with two-coloured bands, was suggestive, but made at a later date. The structure, in fact, over the centuries has undergone numerous changes. Some works that decorated the church, as well as the liturgical furnishings, can still be admired today inside the Civic Museum of Viterbo.