St. John the Baptist was painted by Leonardo da Vinci during 1513 to 1516, when the High Renaissance was metamorphosing into Mannerism, it is believed to be his last painting. This is an oil painting on walnut wood. The original size of the work was 69×57 cm. It is now exhibited at the Musée du Louvre in Paris, France.
The pointing gesture of St. John toward the heavens suggests the importance of salvation through baptism that John the Baptist represents. The work is often quoted by later painters, especially those in the late Renaissance and Mannerist schools. The inclusion of a gesture similar to John’s would increase the importance of a work with a religious conceit.