The palace was built starting in 1738 at the behest of the Marquis of Poppano, Nicola Moscati, unifying two previous buildings received with his wife’s dowry. The project is traditionally attributed to architect Ferdinando Sanfelice. It is, unfortunately, lost the garden that extended to the rear of the palace. The building is characterized by the original interior staircase known as "falcon-winged."
The interior and exterior were richly adorned with stucco decoration of clearly Rococo make, created by Aniello Prezioso to a design by Francesco Attanasio around 1742. The doors leading to the apartments are surmounted by stucco overdoors, with medallions with portrait busts in the center. At the end of the 18th century the palace underwent a makeover that expanded its structure by adding another floor.
On the threshold of the 19th century the family was forced to sell the apartments on the first and second floors. The new owner Tommaso Atienza, known as ‘the Spaniard’ from whom the palace was named, had the frescoes in the rooms, now almost entirely lost, created.
