The church of Pellizzano is first mentioned in a parchment dated May 12, 1264, with the appellation "Sanctae Mariae"; its foundation is therefore to be considered earlier.However, the church was officially consecrated in 1474, at the end of a radical renovation of a sacred building already mentioned in a document dated 1265. Traces of the original structure can be found in a walled-in window in the eastern facade and in the volumes that, in the northern facade surround the grafts that internally house the so-called Canacci Chapel.Subsequent decorative and remodeling works were recorded between the 15th and 16th centuries, when the presence of confraternities (such as the so-called Battuti or Disciplini) favored the work of workers from Lombardy, to whom we owe, for example, the decoration of the right vault (completed in 1545 by Rocco de Redis from Laina) and the realization of the prothyrum (built in 1524 and finished with frescoes in 1533 by Simone de Baschenis from Averara).