Leonardo da Vinci’s embryological drawings of the fetus in the womb and his accompanying observational annotations are found in the third volume of his private notebooks. The drawings of Leonardo’s embryological studies were conducted between the years 1510 – 1512 and were drawn with black and red chalk with some pen and ink wash on paper. These groundbreaking illustrations of the fetus reveal his advanced understanding of human development and demonstrate his role in the vanguard of embryology during the Renaissance. Leonardo expresses the human condition in a nutshell – indeed, his rendition of the womb resembles an opened horsechestnut casing. Inside is the beginning of us all laid bare. Five hundred years ago, this artist and scientist could portray the human mystery with a wonder that is not religious but biological he holds up humanity as a fact of nature.